AIMS/HYPOTHESIS:GPR44 (DP2, PTGDR2, CRTh2) is the receptor for the pro-inflammatory mediator prostaglandin D2 (PGD2) and it is enriched in human islets.In rodent islets, PGD2 is produced in response to glucose, suggesting that the PGD2-GPR44/DP2 axis may play a role in human islet function during hyperglycemia.Consequently, the aim of this work was

Uncertainty affects estimates of the power potential of tidal currents, resulting in large ranges in values reported for sites such as the Pentland Firth, UK.Kreitmair et al.(2019, R.Soc.open sci.6, 180941.(doi:10.1098/rsos.191127)) have examined the effect of uncertainty in bottom friction on tidal power estimates by considering idealized theoreti

Oxidation of cysteine residues of proteins is emerging as an important means of regulation of signal transduction, particularly of protein kinase function.Tools to detect and quantify cysteine oxidation of proteins have been a limiting factor in understanding the role of cysteine oxidation in signal transduction.As an example, the p38 MAP kinase is

Introduction Paraphrenia consists on a syndrome of insidious development with a chronic delirium of great phenomenological richness, predominating productive or delusional-hallucinatory forms and with time it evolves to pure fabulation.Delusions appear in 100% of cases predominating persecution, reference and false identifications.It is a classic t

The geological evolution of the area of M.te Riccio for the Plio-Pleistocene time span has been pointed out.The M.te Riccio area was probably an high OREGA SPRAY during Gelasian-Santernian times.The stratigraphical sequence shows the passage from a coastal marine environment during Pliocene, to a coastal environment during Early Pleistocene (testif